March 3, 2026Open Access

Kaempferitrin Attenuates Lipopolysaccharide‐Induced Cardiac Dysfunction Through Suppression of the NF‐κB/NLRP3 Signaling Pathway

Puntos clave

Cardiac dysfunction improves significantly with kaempferitrin treatment, enhancing heart function.
The study observed a reduction in left ventricular remodeling, indicating improved cardiac health.

PICO estructurado

Población

LPS-induced cardiac dysfunction model

Intervención

Kaempferitrin (Kae)

Resultado

Left ventricular remodeling and cardiac dysfunctionsurrogate

Kaempferitrin demonstrates cardioprotective effects against LPS-induced cardiac dysfunction in a preclinical model by targeting the NF-κB/NLRP3/pyroptosis pathway.

Resumen

This study confirms that Kae alleviates LPS-induced left ventricular remodeling and cardiac dysfunction by suppressing the NF-κB/NLRP3/pyroptosis pathway.

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Discussion

Authors

Hongyu Kuang

Qiang Li

Min Chen

Journals

Immunity Inflammation and Disease

Actions

Institutions

Chongqing Medical University

Children's Hospital of Chongqing Medical University

References and Citations

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Building similarity graph...

Analyzing shared references across papers

Kaempferitrin Attenuates Lipopolysaccharide‐Induced Cardiac Dysfunction Through Suppression of the NF‐κB/NLRP3 Signaling Pathway

Puntos clave

PICO estructurado

Resumen

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Cite this study