March 3, 2026Open Access

Alterations in the DTI-ALPS index and choroid plexus volume as brain–immune interfacing indicators in neuropsychiatric lupus erythematosus with inflammatory phenotype

Key Points

The DTI-ALPS index and choroid plexus volume are potential biomarkers for neuropsychiatric lupus erythematosus (NPSLE), indicating unique subtypes.
Both indicators appear to reflect underlying mechanisms of central nervous system damage in this condition, thus expanding diagnostic tools.
Assessment utilized neuroimaging techniques to measure these biomarkers in patients with inflammatory phenotype characteristics.
These findings highlight the need for further investigation into brain-immune interfaces to improve understanding and treatment.

Abstract

In conclusion, the DTI-ALPS index and CP volume demonstrate significant potential as neuroimaging biomarkers for NPSLE. They hold promise for differentiating between NPSLE subtypes and shedding light on the underlying mechanisms of central nervous system damage.

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Authors

Huiyang Liu

Hongxia Li

Bailing Tian

Journals

Lupus Science & Medicine

Actions

Institutions

China Medical University

First Hospital of China Medical University

Siemens Healthcare (United States)

References and Citations

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Building similarity graph...

Analyzing shared references across papers

Alterations in the DTI-ALPS index and choroid plexus volume as brain–immune interfacing indicators in neuropsychiatric lupus erythematosus with inflammatory phenotype

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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