Total Testosterone Measured by Liquid Chromatograph‐Tandem Mass Spectrometry Refines Diagnosis of Biochemical Hyperandrogenism and Better Identifies Subgroup at Genuine Risk of Adverse Fertility Outcomes in Women With Polycystic Ovary Syndrome

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• Biochemical hyperandrogenism is better diagnosed with total testosterone levels measured by liquid chromatography-tandem mass spectrometry,
• Data analysis from both the NIH and Chinese Clinical Trial Registry emphasizes the importance of accurate testosterone measurement in identifying at-risk women.
• This approach helps pinpoint individuals who may face adverse fertility outcomes due to polycystic ovary syndrome,
• Improving diagnostic precision could lead to more effective management strategies for reproductive health in women suffering from PCOS.

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