Camptothecin-PHA nanoparticles attenuate drug-induced gut microbiome dysbiosis and metabolic toxicity

Key Points

• Nanoparticles reduce metabolic toxicity in the gut microbiome, promoting microbial balance.
• This treatment shows effective mitigation of negative effects on intestinal flora and serum metabolism.
• Analysis of a novel nanomaterial demonstrated its potential in promoting metabolic safety during therapy.
• Implications suggest that addressing microbial balance may enhance overall treatment safety.

Abstract