Exploring the Dynamics of Ischemia and Reactive Hyperemia With Skeletal Muscle Blood Oxygen Level Dependent MRI in Patients With Peripheral Artery Disease, Age‐Matched Controls, and Young Healthy Subjects

Key Points

• Ischemia impacts vascular function, influencing blood supply to skeletal muscle and leading to altered oxygen dynamics.
• The analysis utilized blood oxygen level dependent MRI to assess these changes across varied subject groups.
• Peripheral artery disease patients exhibited distinct reactive hyperemia responses compared to age-matched controls and healthy individuals.
• Findings highlight potential diagnostic indicators for vascular health, necessitating further exploration in diverse populations.