March 3, 2026Open Access

Defining Relapse and Disease Activity in Neurosarcoidosis

Puntos clave

This review identifies substantial heterogeneity in measuring disease activity in neurosarcoidosis, complicating treatment decisions.
Many studies lack formal definitions for disease activity metrics, which can lead to inconsistent reporting across research.
The proposed framework integrates multiple assessment domains to better characterize disease activity in neurosarcoidosis.
Standardization of these practices may enhance clinical reasoning, leading to better communication among healthcare providers.

Resumen

A systematic review highlighted substantial heterogeneity in how CNS neurosarcoidosis disease activity is measured, with many studies lacking formal definitions and often reporting activity only within isolated domains. This proposed framework integrates multiple domains to comprehensively characterize CNS neurosarcoidosis disease activity. With further validation, this approach has the potential to standardize research practices and improve clinical reasoning and communication.

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Authors

Greer Waldrop

Susana C. Dominguez Penuela

Paula Barreras

Journals

Neurology Clinical Practice

Actions

Institutions

Johns Hopkins University

University of California, San Francisco

Johns Hopkins Medicine

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Defining Relapse and Disease Activity in Neurosarcoidosis

Puntos clave

Resumen

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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