Clinical resolution of oral lichenoid lesions after amalgam replacement: A systematic review and meta-analysis of observational studies

Key Points

• Resolution of oral lichenoid lesions shows significantly higher odds after amalgam replacement, suggesting effective intervention.
• Pooled data indicates a notable increase in resolution odds, yet substantial heterogeneity raises questions about reliability.
• Systematic review involved observational studies analyzing the impact of amalgam replacement on oral lichenoid lesions.
• Further prospective studies are needed to standardize diagnostic criteria and refine effect size estimates.

Abstract