MicroRNA hepatocellular carcinoma detect: discriminant function based on a circulating panel of microRNA for accurate diagnosis of hepatocellular carcinoma patients on top hepatitis C virus infection

Key Points

• Detection rates for HCC are improved using the miR-HCC Detect score, which surpasses individual biomarker performance.
• The analysis shows that circulating miRNAs serve as effective noninvasive biomarkers for hepatocellular carcinoma.
• Assessment shows that hepatitis C virus infection status influences the diagnostic accuracy of the microRNA panel.
• This study highlights the need for further validation of noninvasive diagnostic tools for early HCC detection.

Abstract