March 3, 2026Open Access

Impact of mismatch repair genes deficiency on survival outcomes and establishment of a novel prognostic prediction model for stage I-II endometrial carcinoma

Key Points

Early-stage endometrial carcinoma patients with mismatch repair deficiency experience poorer survival outcomes.
The study indicates that combining MMR status with clinicopathological factors can create a novel prognostic prediction model.
Full molecular sequencing is recommended to determine the prognostic significance of MMR status in patients.
Further prospective research is needed to validate the findings and refine the prognostic model.

Abstract

Among early-stage EC patients, MMRd group had poorer survivals. Combination of MMR status and other clinicopathological factors could establish a new prognostic model. Prospective studies with full molecular sequencing to determine the prognostic significance of MMR status are needed.

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Authors

Wenhui Wang

Zihan Yan

Yuanyuan Chen

Journals

Taiwanese Journal of Obstetrics and Gynecology

Actions

Institutions

Chinese Academy of Medical Sciences & Peking Union Medical College

Peking Union Medical College Hospital

Cangzhou Central Hospital

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Impact of mismatch repair genes deficiency on survival outcomes and establishment of a novel prognostic prediction model for stage I-II endometrial carcinoma

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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