Pre-treatment ALI and TL jointly provide robust and complementary prognostic information in ESCC patients receiving neoadjuvant immunochemotherapy. Low ALI combined with high TL identifies a biologically aggressive subset with poor pathologic response and inferior survival. Integration of ALI and TL may facilitate risk-adapted perioperative strategies and personalized treatment optimization.
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Yizhou Huang
Maohui Chen
Zhenyuan Yang
Frontiers in Immunology
SHILAP Revista de lepidopterología
Lanzhou University
Fujian Medical University
First Hospital of Lanzhou University
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Huang et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69a75cacc6e9836116a25bdd — DOI: https://doi.org/10.3389/fimmu.2026.1724061
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