March 3, 2026Open Access

Multi‐omic expression of the VEGF family relates to Alzheimer's disease across diverse populations

Key Points

Alzheimer's disease shows significant relationships with vascular endothelial growth factor expression across populations.
The largest multi-omic analysis included participants from four diverse populations, supporting previous findings.
Quantification of VEGF genes was performed in four different brain regions to examine genetic contributions.
These insights may highlight genetic targets for further investigation in Alzheimer's disease treatment strategies.

Abstract

Vascular endothelial growth factor (VEGF) genes and proteins were quantified in four different brain regions. Samples included participants from four different populations. Previously observed effects were replicated in diverse populations. This study is the largest multi-omic study of the vascular endothelial growth factor (VEGF) genes among Alzheimer's disease (AD) participants from diverse populations.

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Authors

Julia B. Libby

Kacie D. Deters

Nilüfer Ertekin‐Taner

Journals

Alzheimer s & Dementia

Actions

Institutions

University of California, Los Angeles

University of California, San Francisco

University of Wisconsin–Madison

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Multi‐omic expression of the VEGF family relates to Alzheimer's disease across diverse populations

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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