March 3, 2026Open Access

Differential cytotoxicity mechanisms of copper complexed with disulfiram for combination chemotherapy in human endometrial cancer cells

Puntos clave

Copper complexes demonstrate varied effects on cytotoxicity in endometrial cancer cells.
The interaction between CuCl and CuCl2 with disulfiram was analyzed for therapeutic implications.
A focus on molecular interactions reveals potential mechanisms behind observed cytotoxic effects.
Insights may highlight novel strategies for tackling endometrial cancer through combination therapies.

Resumen

These findings indicate differential effects of CuCl and CuCl2 when complexed with DSF in human endometrial cancer cells. Given the pressing need for innovative approaches to tackle endometrial cancer, we believe our findings contribute valuable insights into the molecular interactions and therapeutic potentials of DSF/copper complexes.

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Cite this study

Liu et al. (Thu,) studied this question.

www.synapsesocial.com/papers/69a75d2bc6e9836116a26bf1 — DOI: https://doi.org/10.3389/fonc.2026.1760903

Authors

Peng-Sin Liu

Zih-Syuan Wu

Shih‐Ming Huang

Journals

Frontiers in Oncology

Actions

Institutions

National Defense Medical Center

National Defense Medical College

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Differential cytotoxicity mechanisms of copper complexed with disulfiram for combination chemotherapy in human endometrial cancer cells

Puntos clave

Resumen

Citation Network

Connected Papers

Discussion

Cite this study

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion