The interaction of fibrinolysis and the complement system in patients with acute pulmonary embolism, treated with ultrasound-assisted catheter-directed thrombolysis

Key Points

• Acute pulmonary embolism treatment impacts both fibrinolysis and the complement system, leading to enhanced therapeutic effectiveness.
• Key evidence shows that ultrasound-assisted catheter-directed thrombolysis improves clinical outcomes in patients with acute pulmonary embolism.
• Assessment using data from acute pulmonary embolism patients demonstrates the interplay between fibrinolysis and immune responses during treatment.
• The findings highlight the potential for integrated therapeutic strategies, though further validation in diverse cohorts is needed.