Acetate ameliorates glucolipid metabolic dysregulation and neuroinflammation in diabetic cognitive impairment via enhanced mitophagy

Key Points

• Acetate notably enhances mitophagy, leading to improved glucolipid metabolism and reduced neuroinflammation.
• A significant reduction in neuroinflammation markers was observed, suggesting positive cognitive outcomes.
• Analysis focused on diabetic models, linking improved metabolic health with cognitive function.
• The findings may enable new therapeutic strategies for managing diabetic cognitive impairment.