March 3, 2026Open Access

A Multi-Mineral Intervention Improves Intestinal Permeability in Patients with Ulcerative Colitis: Results from a 90-Day Pilot Trial

Key Points

Intestinal permeability improved significantly after 90 days of Aquamin supplementation.
Urinary mannitol excretion decreased, indicating better gut barrier function in patients with ulcerative colitis.
Observational pilot trial analyzed the effects of multi-mineral supplementation on gut health metrics.
Supports Aquamin as a promising adjunct therapy, highlighting the need for further studies in diverse populations.

Abstract

Aquamin ® supplementation for 90 days reduced intestinal permeability in ulcerative colitis patients, as measured by urinary mannitol excretion. The intervention was well tolerated, suggesting Aquamin ® may be a safe, promising adjunct for enhancing gut barrier function in UC management.

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Authors

Durga Attili

D. Kim Turgeon

Shannon D. McClintock

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Institutions

University of Michigan

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A Multi-Mineral Intervention Improves Intestinal Permeability in Patients with Ulcerative Colitis: Results from a 90-Day Pilot Trial

Key Points

Abstract

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Discussion

Authors

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