Class-level drug safety surveillance in hospital practice: A pharmacovigilance analysis of 84 therapeutic subclasses from a South Asian tertiary care center

Key Points

• Establishes baseline risk estimates for therapeutic subclasses in pharmacovigilance environments, highlighting the need for improved safety monitoring.
• Finds that certain drug classes show disproportionately high-risk profiles, indicating areas for deeper investigation and intervention.
• Assessment indicates the robustness of the Proportional Reporting Ratio (PRR) and Reporting Odds Ratio (ROR) as tools for drug safety evaluation.
• Supports the need for enhanced drug safety protocols in developing regions to counteract high-risk drug class effects.

Abstract