Does reducing tidal volume resolve glycopyrrolate-induced tachycardia in the left lateral decubitus position under mechanical ventilation?
1 28-year-old woman who developed drug-induced tachycardia in the left lateral decubitus (LLD) position following intravenous administration of glycopyrrolate under mechanical ventilation
Reduction of tidal volume from 8 to 6 mL/kg
Resolution of tachycardia
Adopting a low tidal volume ventilation strategy (6 mL/kg) may attenuate drug-induced tachycardia occurring in the left lateral decubitus position under mechanical ventilation.
A 28-year-old woman developed drug-induced tachycardia in the left lateral decubitus (LLD) position following intravenous administration of glycopyrrolate. The tachycardia was unresponsive to esmolol, labetalol, and fentanyl but resolved unexpectedly after the tidal volume was reduced from 8 to 6 mL/kg. Drug-induced tachycardia or arrhythmia occurring in the LLD position under mechanical ventilation may be attenuated by adopting a low tidal volume ventilation strategy (6 mL/kg).
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Seung Ju Ahn
So Young Lee
The Ewha Medical Journal
SHILAP Revista de lepidopterología
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Ahn et al. (Fri,) studied this question.
www.synapsesocial.com/papers/69a75f2ac6e9836116a2a581 — DOI: https://doi.org/10.12771/emj.2025.00983