Alcohol use disorder is associated with altered frontomedial phase-amplitude coupling strength during resting state

Key Points

• Altered phase-amplitude coupling strength indicates potential disruptions in brain connectivity.
• Phase-amplitude coupling changes were identified during resting state analyses, highlighting abnormal neural dynamics.
• Analysis of brain activity shows significant differences in individuals with alcohol use disorder compared to healthy controls.
• Understanding these alterations may offer insights into the neurological impact of alcohol use disorder and potential treatment pathways.