μPharma: A microfluidic, AI-driven pharmacotyping platform for single-cell drug sensitivity prediction in leukemia

Key Points

• Single-cell drug sensitivity predictions highlight significant variability in responses among leukemia cells, indicating some are more resistant to treatment.
• The method delivers predictions with over 85% accuracy based on AI algorithms applied to analyses of cell responses to various drugs.
• Using a microfluidic approach, the platform enables the assessment of thousands of individual cells under controlled conditions for novel insights.
• Findings may enhance personalized medicine efforts for leukemia, indicating tailored treatments could improve outcomes significantly.