RAD51 promotes osteogenic differentiation and inhibits DNA damage in osteoporosis though regulating cGAS-STING signaling pathway

Key Points

• Osteogenic differentiation was significantly promoted by RAD51, enhancing bone formation.
• DNA damage was inhibited through the regulation of the cGAS-STING signaling pathway by RAD51.
• This assessment utilized various experimental methods to explore RAD51's functions in osteoporosis.
• These findings highlight RAD51 as a potential target for new osteoporosis therapies, necessitating further research.

Abstract