Effects of crocetin, a constituent of saffron, on indomethacin-induced gastric ulcer and related anxiety-like behavior in rats

Key Points

• Crocetin significantly reduces gastric ulcer severity, improving animal welfare.
• In rats administered indomethacin, treated groups showed 50% less ulceration compared to controls.
• Assessment using a rat model showed the behavioral effects alongside ulcer healing.
• Findings imply that saffron compounds like crocetin may provide dual therapeutic effects.