March 3, 2026Open Access

Nonlinear association between hematocrit and 3-month outcome after acute ischemic stroke: identification of threshold effects in males

Key Points

Adverse outcomes increase with low hematocrit in males after acute ischemic stroke, indicating a potential threshold effect.
In males, hematocrit levels below a specific value show a significant link to worse 3-month outcomes.
The analysis focused on the nonlinear relationship, revealing different outcomes based on sex in acute ischemic stroke patients.
Findings underscore the importance of considering sex differences in treatment and management strategies for stroke patients.

Abstract

This study revealed a nonlinear, sex-specific relationship between HCT and 3-month outcome in AIS patients. In male patients, HCT levels below the threshold were inversely associated with adverse outcome, while no significant association was observed in female patients.

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Authors

Xiaomin Liang

Qian Wang

Zemao Xing

Journals

SHILAP Revista de lepidopterología

Frontiers in Medicine

Actions

Institutions

Chinese University of Hong Kong, Shenzhen

Shenzhen Second People's Hospital

References and Citations

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Building similarity graph...

Analyzing shared references across papers

Nonlinear association between hematocrit and 3-month outcome after acute ischemic stroke: identification of threshold effects in males

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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