The Gut Microbiome As the Link between Antibiotic Exposures and Cytomegalovirus Viremia after Hematopoietic Cell Transplantation in Children

Key Points

• Cytomegalovirus viremia is more likely in children exposed to antibiotics following hematopoietic cell transplantation.
• A significant correlation was observed between microbiome diversity and levels of cytomegalovirus viremia in this population.
• Observational analysis across children who underwent hematopoietic cell transplantation evaluated antibiotic use and viremia.
• Findings support the potential for microbiome modulation strategies to mitigate cytomegalovirus outcomes in pediatric transplantation.