Ceramides may Play a Central Role in the Pathogenesis of Alzheimer's Disease: a Review of Evidence and Horizons for Discovery

Key Points

• Ceramides may significantly influence the pathogenesis of Alzheimer's disease—affecting neuronal health.
• Research indicates a link between ceramide levels and neuroinflammation, impacting disease progression.
• Observational analysis of multiple studies suggests that ceramides act as crucial biomarkers for Alzheimer's disease.
• Understanding how ceramides contribute to Alzheimer's may open up new therapeutic avenues for treatment.