Background and purpose: Parkinson’s disease is a neurodegenerative disorder cha racterized by motor symptoms such as tremor, rigidity and bradykinesia. However, it can also lead to non-motor symptoms such as cognitive impairments and sarcopenia. The aim of this study is to evaluate the relationship between screening and diagnostic methods for sarcopenia and temporal muscle thickness in Parkinson’s disease patients, and to assess the utility of temporal muscle thickness measurement as an indicator of sarcopenia. Methods: An observational study was conducted with Parkinson’s disease patients in a single neurology clinic. A total of 38 patients were included. Temporal muscle thickness was measured manually using brain computed tomography and muscle strength was assessed with handheld dynamometer. Malnutrition risk, sarcopenia risk and functional disease stage (Movement Disorders Society-Unified Parkinson’s Disease Rating Scale, Hoehn and Yahr stage) were also evaluated in entire group. Results: The mean temporal muscle thickness and handgrip strength were 6.12±1.05 mm and 18.30±5.55 kg respectively. Mean disease duration was 8.13±3.11 years and the median H p = 0,046), a SARC-F-pontszám (r = −0,738; p < 0,001), az NRS-2002-pontszám (r = −0,379; p = 0,019), valamint a kézszorító erő (r = 0,323; p = 0,048) között. A többszörös lineáris regressziós analízis kimutatta, hogy a sarcopenia kockázata önállóan összefüggött az átlagos halántékizom-vastagsággal Parkinson-kóros betegeknél (β = −0,704; p < 0,001), míg a kézszorító erő önállóan összefüggött az életkorral (β = −0,123; p = 0,010), a nemmel (β = 0,881; p < 0,001) és a sarcopenia kockázatával (β = −0,371; p < 0,001). Következtetés – A halántékizom vastagságának mérése agyi komputertomográfia segítségével Parkinson-kóros betegeknél hasznos módszer lehet az izomtömeg meghatározására és a sarcopenia kezelésének támogatására.
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Nedim ONGUN
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Nedim ONGUN (Thu,) studied this question.