Synthesis and structural characterization of zinc(II) carboxylate complexes with antibacterial and in vivo antibiofilm activities

Key Points

• Zinc(II) carboxylate complexes showed significant antibacterial activities against multiple pathogens, reducing growth effectively.
• The lowest observed minimum inhibitory concentration for these complexes was 5 µM, highlighting their potency as antibacterial agents.
• Assessment of structural characterization included techniques like NMR and X-ray crystallography, revealing complex molecular arrangements.
• These findings support the development of zinc(II) complexes as effective agents for tackling bacterial infections and biofilms.