Combination of Hypoxia-Preconditioned ADSCs and Deferoxamine Can Speed Up the Healing of Diabetic Wounds by Promoting Angiogenesis and Regulating Macrophage Polarization

Key Points

• Healing is significantly accelerated by the combination of hypoxia-preconditioned ADSCs and deferoxamine, enhancing tissue repair.
• In diabetic wounds, the treatment increases angiogenesis, promoting new blood vessel formation essential for healing.
• This study utilizes a dual approach with hypoxia-preconditioned ADSCs that enhances macrophage polarization for better wound outcomes.
• Findings may indicate a potential therapeutic strategy for diabetic patients with slow-healing wounds.