A surface layer protein OTC from Enterococcus faecium WEFA23 contributes to reinforcing the intestinal barrier and modulating gut microbiota and metabolic profiles in Listeria monocytogenes-infected mice

Key Points

• Reinforcement of the intestinal barrier is observed, indicating enhanced protection against pathogen invasion.
• Significant modulation of gut microbiota occurs, revealed by assessing microbial diversity and composition.
• Analysis of metabolic profiles demonstrates notable shifts, connecting microbial changes to host metabolism.
• Findings imply that targeting Enterococcus faecium may enable new strategies for gut health enhancement.