Plasma untargeted lipidomics based on UHPLC-Orbitrap-MS reveals potential biomarkers and the pathogenesis involved in Mycoplasma bovis pneumonia

Key Points

• Mycoplasma bovis pneumonia is linked to specific lipid biomarkers in plasma, which may aid in diagnosis.
• The analysis identified various lipid metabolic pathways influenced by the infection, highlighting potential therapeutic targets.
• Assessment using UHPLC-Orbitrap mass spectrometry enabled the extraction of untargeted lipid profiles from plasma samples.
• Findings suggest that lipid profiles might play a crucial role in understanding pneumonia pathogenesis and treatment approaches.