The clinical efficacy and mechanism of iTBS combined with working memory training on negative symptoms of schizophrenia based on fNIRS: A randomized controlled study

Key Points

• Negative symptoms improved significantly with iTBS plus working memory training in participants.
• The study reported an effect size of 0.75, indicating a meaningful clinical benefit.
• Randomized controlled trial assessed changes in negative symptoms using fNIRS for brain activity measurement.
• This research highlights the potential role of combined therapies in enhancing treatment for schizophrenia.