Lattice Instability Drives Formation of Protofilament Clusters at the Microtubule Plus End Tips

Key Points

• Protofilament clusters form due to lattice instability at microtubule ends, impacting cell structure.
• Observation of these clusters highlights the role of instability, influencing microtubule behavior during growth.
• Detailed visual analysis of microtubule dynamics using advanced imaging techniques supports these findings.
• The findings indicate that controlling lattice stability may help in understanding cellular processes and therapies.