Validation and pharmacological evaluation of bioactive constituents from Silybum marianum seeds (milk thistle) using in vitro and in silico approaches

Key Points

• Bioactive constituents show promising pharmacological effects on various health aspects,
• Key evaluation metrics highlight significant activity against certain biological targets in vitro.
• In vitro and in silico assessments were conducted to explore the bioactivities of Silybum marianum extracts.
• Findings suggest further investigation into the therapeutic potential of milk thistle bioactives is warranted.