Fecal metabolic biomarkers associated with insomnia severity: A study on 5-hydroxyindoleacetic acid, octopamine, oleoylethanolamide, and elaidic acid

Key Points

• Insomnia severity correlates with specific fecal biomarkers, highlighting their potential as diagnostic tools.
• Among the biomarkers, 5-hydroxyindoleacetic acid and oleoylethanolamide show significant associations with insomnia levels.
• The analysis utilizes a broad range of metabolites found in fecal samples to assess insomnia severity.
• These findings underscore the need for further exploration of fecal biomarkers in sleep disorders.