March 3, 2026Open Access

Hepatitis B virus RNA and hepatitis B surface antigen kinetics predict treatment outcomes in children with chronic hepatitis B

Puntos clave

HBeAg seroconversion can be better predicted by early pgRNA kinetics in children.
HBsAg loss is forecasted more effectively with HBsAg dynamics along with patient age data.
Utilizing both pgRNA and HBsAg monitoring may enhance treatment personalization in chronic hepatitis B cases.
This strategy highlights the potential for improved management and outcomes in pediatric hepatitis B therapy.

Resumen

Early pgRNA kinetics more accurately predict HBeAg seroconversion, whereas HBsAg dynamics forecast HBsAg loss more effectively, particularly when combined with patient age. This complementary monitoring strategy provides a clinically applicable tool for optimizing personalized management in children with CHB.

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Authors

Xi Peng

Yunan Chang

Jiaying Wu

Journals

Frontiers in Cellular and Infection Microbiology

Actions

Institutions

Chongqing Medical University

Dalian Medical University

Second Affiliated Hospital of Chongqing Medical University

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Hepatitis B virus RNA and hepatitis B surface antigen kinetics predict treatment outcomes in children with chronic hepatitis B

Puntos clave

Resumen

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

Cite this study