A ratiometric fluorescent dual-mode amplification nanosensor based on pH and oxygen testing for ultrasensitive glucose detection

Key Points

• Glucose detection sensitivity was significantly enhanced by utilizing a dual-mode approach with pH and oxygen.
• The ratiometric fluorescent nanosensor shows a notable increase in detection capabilities under varying conditions.
• Assessment of this novel glucose detection method highlights its potential for future clinical applications.
• Further validation in diverse biological systems may be necessary to confirm effectiveness beyond controlled settings.