Can the Caval Aortic Index and ultrasound measurements of IVC and aorta predict adverse perinatal outcomes in diabetic pregnant women?
220 pregnant women, comprising 120 with diabetes mellitus (pre-gestational, diet-regulated gestational, and insulin-regulated gestational diabetes) and 100 healthy controls.
Ultrasound measurement of inferior vena cava (IVC) and aortic (Ao) diameters, and calculation of the Caval Aortic Index.
Healthy pregnant controls (n=100).
Functional changes in IVC and aorta diameters and prediction of adverse perinatal outcomes.surrogate
IVC and aortic diameters are significantly higher in pregnant women with diabetes compared to healthy controls, suggesting potential utility of these measurements in assessing vascular changes.
Aims: Diabetes mellitus (DM), including gestational (GDM) and pregestational diabetes (pre-GDM), adversely affects maternal and fetal outcomes due to hyperglycemia and vascular changes. The Caval Aortic Index, a non-invasive measure of blood volume, could provide insights into these complications. In our study, we aimed to determine the functional changes in inferior vena cava (IVC) and aorta (Ao) diameters as well as the importance of caval aortic index in predicting perinatal outcomes in diabetic pregnant women.Methods: This prospective case-control study included 120 DM patients and 100 controls. DM patients were divided into pre-GDM, diet-regulated GDM, and insulin-regulated GDM groups. Ultrasound measurements of inferior vena cava and aortic diameters were performed, alongside Doppler evaluations. Statistical analyses were conducted to assess the association of these parameters with adverse perinatal outcomes.Results: Although the IVC and aortic diameters of the pregnant women with DM were higher compared to the control group and a statistically significant difference (p
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Gülşan Karabay
Zeynep Şeyhanlı
Ahmet Arif Filiz
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Karabay et al. (Thu,) studied this question.