Effects of PCSK9 inhibitors on vascular function, lipid profile, and cardiovascular outcomes in patients with peripheral artery disease: A systematic review and meta-analysis

Key Points

• PCSK9 inhibitors significantly improve vascular function, indicating better cardiovascular health.
• Meta-analysis shows lipid profile improvements with PCSK9 inhibitors across patients with peripheral artery disease.
• Observational analysis of various studies on patients with peripheral artery disease highlights important outcomes of treatment.
• Findings suggest PCSK9 inhibitors could play a crucial role in managing vascular health and cardiovascular events.