Single-cell transcriptomics reveals the toxic mechanism and therapeutic target of ubiquitously distributed mycotoxin deoxynivalenol

Key Points

• Deoxynivalenol exposure results in significant alterations at the single-cell level, highlighting its toxic impact.
• Key findings reveal that altered gene expression patterns in cells can be linked to specific cellular pathways affected by deoxynivalenol.
• Utilizing single-cell transcriptomics enables detailed observations of individual cell responses to mycotoxin exposure.
• This study underscores the potential for targeted therapies against deoxynivalenol, emphasizing the need for further exploration in clinical settings.