Patients with mitral annular calcification had a 10-year mortality of 55.1% compared to 38.3% in those without, representing a significantly higher risk of death after aortic valve replacement.
Cohort
No
Does the presence of mitral annular calcification or extensive aortic arch calcification independently predict higher mortality in patients with severe aortic stenosis undergoing aortic valve replacement?
636 patients with severe aortic stenosis (aortic valve area <1.0 cm2 or indexed AVA <0.6 cm2/m2, and peak transaortic velocity ≥4.0 m/s, or mean transaortic pressure gradient ≥40 mmHg) undergoing surgical or transcatheter aortic valve replacement. Median age 72 years, 56.6% male, based in Korea.
Presence of mitral annular calcification (MAC) or extensive aortic arch calcification (AAC ≥180°)
Absence of MAC and/or non-extensive/no AAC (<180°)
All-cause mortalityhard clinical
Mitral annular calcification and aortic arch calcification are markers of advanced age and comorbidity rather than independent predictors of mortality after aortic valve replacement.
Mitral annular calcification and aortic arch calcification are more markers of advanced age and comorbidity rather than a direct determinant of post-aortic valve replacement survival.It is therefore essential to optimize overall comorbidity management for this patient subgroup.
Building similarity graph...
Analyzing shared references across papers
Loading...
Seok Hyun Kim
Soo Yong Lee
Jin Hee Choi
Korean Circulation Journal
Pusan National University Yangsan Hospital
Building similarity graph...
Analyzing shared references across papers
Loading...
Kim et al. (Thu,) conducted a cohort in Severe Aortic Stenosis (n=636). Aortic Valve Replacement vs. No Aortic Annular Calcification or Mitral Annular Calcification was evaluated on All-cause mortality (RR 1.43, 95% CI 1.19-1.72, p=0.007). Patients with mitral annular calcification had a 10-year mortality of 55.1% compared to 38.3% in those without, representing a significantly higher risk of death after aortic valve replacement.
www.synapsesocial.com/papers/69b3aaa802a1e69014ccb7de — DOI: https://doi.org/10.4070/kcj.2025.0266
Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context: