What type of study is this?

This is a Cohort Study study (also classified as: Human Clinical Trial).

What question did this study set out to answer?

The study aimed to determine if a gene expression profile can predict SLN positivity in melanoma patients.

March 15, 2026

The integrated 31-gene expression profile test identifies low-risk patients with cutaneous melanoma who can forego the SLNB procedure: results from a prospective, multicenter trial

Puntos clave

The study aimed to determine if a gene expression profile can predict SLN positivity in melanoma patients.
Conducted a multicenter prospective trial
Evaluated 31-gene expression profile test in melanoma patients
Assessed SLN positivity and recurrence-free survival (RFS) outcomes
The gene expression profile test accurately predicted SLN positivity
Patients who avoided SLNB had high recurrence-free survival (RFS)
Identified a subset of low-risk melanoma patients

Resumen

In this multi-center prospective study, the i31-SLNB accurately predicted SLN positivity, and patients who avoided SLNB based on i31-SLNB results had high RFS. Thus, the i31-SLNB identifies low-risk patients who may consider foregoing the SLNB procedure.

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Authors

Timothy L. Beard

J. Michael Guenther

Stanley P. Leong

Journals

Future Oncology

Actions

Institutions

University of California, Irvine

University of Tennessee at Knoxville

California Pacific Medical Center

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

The integrated 31-gene expression profile test identifies low-risk patients with cutaneous melanoma who can forego the SLNB procedure: results from a prospective, multicenter trial

Puntos clave

Resumen

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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