Event-related potentials and behavioural correlates of cognitive functions in MS: An EEG study during symbol digit modalities test

Puntos clave

• To explore the relationship between event-related potentials and cognitive functions in patients with multiple sclerosis (pwMS) during an EEG-SDMT task.
• EEG-SDMT paradigm used to assess cognitive performance
• Event-related potentials measured while participants performed a symbol digit modalities test
• Comparative analysis of latencies and response times among participants with MS
• P5 latency was longer in pwMS but did not differentiate cognitive impairment levels
• Response times were found to be reliable indicators of cognitive performance
• Study suggests early stages may not capture higher-order cognitive deficits effectively

Resumen