Phenotypic profiling of pristane‐induced mimicking human systemic lupus erythematosus in Macaca fascicularis

Puntos clave

• The aim is to explore the translational potential of a nonhuman primate model of systemic lupus erythematosus (SLE).
• Induced SLE through pristane administration in Macaca fascicularis
• Monitored autoantibody levels and multisystem involvement
• Assessed model's reproducibility and translational potential
• Confirmed reproducibility of autoantibody elevation
• Observed multisystem involvement mimicking human SLE
• Demonstrated utility for assessing novel therapeutic approaches

Resumen