Trends and Predictors of Premature Termination of Cardiovascular Trials

Key Points

• This research aims to identify trends and factors leading to the premature termination of cardiovascular trials.
• Analysis of historical cardiovascular trials
• Identification of key predictors of termination
• Quantitative assessment of trends over time
• Many cardiovascular trials terminate before completion, leading to wasted resources.
• Specific predictors of premature termination were identified.
• Trends over time indicate increasing rates of early discontinuation.

Abstract