Protostane triterpenes from the rhizome of Alisma plantago-aquatica

Puntos clave

• To isolate and characterize new protostane triterpenes from the rhizome of Alisma plantago-aquatica and evaluate their bioactivities.
• Isolation of compounds from dried rhizome using chemical methods
• Characterization of structures through spectroscopic analysis and single crystal X-ray diffraction
• Assessment of cytotoxicity against six human tumor cell lines
• Evaluation of hepatoprotective and anti-inflammatory activities
• Identification of a new compound, 11-deoxy-25-O-ethylalisol A
• Four known analogues were also isolated
• Compounds exhibited variable cytotoxicity against the tumor cell lines
• Potential hepatoprotective and anti-inflammatory effects were observed

Resumen