Quantifying multi-expert variability enables a probabilistic GS and clinically relevant thresholds for CT-MRI registration. This benchmark reflects human performance and provides a framework for algorithm validation. An AI-driven CB algorithm demonstrated high reliability, reduced operator dependence, and may streamline SRS workflows.
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Valeria Faccenda
Denis Panizza
Valentina Pinzi
Physica Medica
University of Padua
Institut Gustave Roussy
University of Milano-Bicocca
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Faccenda et al. (Thu,) studied this question.
www.synapsesocial.com/papers/69bf86ecf665edcd009e915f — DOI: https://doi.org/10.1016/j.ejmp.2026.105765