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This evaluation examines the cost-effectiveness of oral immunotherapy treatments for peanut allergy compared to no treatment.

March 22, 2026Open Access

Cost-Effectiveness of Oral Immunotherapy Treatments vs No Treatment for Peanut Allergy in Children

Key Points

This evaluation examines the cost-effectiveness of oral immunotherapy treatments for peanut allergy compared to no treatment.
Conducted an economic evaluation of PPOIT and OIT for peanut allergy.
Compared the treatments' effects on remission and quality of life.
Analyzed treatment product pricing's impact on cost-effectiveness.
Both PPOIT and OIT were found to be cost-effective versus no treatment.
OIT provided a larger effect size without a clinically meaningful difference.
Prioritizing quality-adjusted life years (QALYs) favors PPOIT in terms of best value.

Abstract

This economic evaluation found that for remission, both PPOIT and OIT were cost-effective and good value compared with no treatment, with OIT associated with a larger effect size but no clinically meaningful difference. When QALYs are prioritized, PPOIT offers the best value. Key factors associated with cost-effectiveness were treatment product pricing and patient quality of life.

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Discussion

Authors

Li Huang

Melanie Lloyd

Adam Franz

Journals

JAMA Network Open

Actions

Institutions

The University of Melbourne

The University of Western Australia

The University of Adelaide

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Cost-Effectiveness of Oral Immunotherapy Treatments vs No Treatment for Peanut Allergy in Children

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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