Conclusion:Our case report opens an interesting therapeutic field for the use of complement blockers for the treatment of C3G.From this point-of view, the current case report , shows that iptacopan is highly effective regarding the reduction of proteinuria and recovery and stabilization of kidney function and is well tolerated.Our case report suggests that even under the 10-month monotherapy, iptacopan may become a promising oral treatment option for C3G.I have no potential conflict of interest to disclose.I did not use generative AI and AI-assisted technologies in the writing process.
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Kento Kitamura
Masahiro Okabe
Takaya Sasaki
Kidney International Reports
Juntendo University
Jikei University School of Medicine
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Kitamura et al. (Wed,) studied this question.
www.synapsesocial.com/papers/69c770888bbfbc51511e0a67 — DOI: https://doi.org/10.1016/j.ekir.2026.104796