纳米脂质体递药系统在肿瘤治疗中的跨膜效率提升策略

Key Points

• This paper explores the challenges and strategies to enhance the transmembrane efficiency of nano-liposomes in cancer treatment.
• Overview of nano-liposome structure and application in tumor therapy.
• Analysis of factors affecting transmembrane efficiency such as uptake pathways and intracellular transport bottlenecks.
• Review of three major strategies: functionalization for active targeting, physical field applications, and biomimetic engineering.
• Identified key factors hindering transmembrane efficiency of liposomes.
• Highlighted advancements in surface modifications and triggering techniques to enhance efficiency.
• Discussed challenges in current research and potential future trends in nano-drug development.

Abstract