溶酶体贮积症与鞘脂等脂质代谢和转运

Key Points

• This research aims to understand how lysosomes regulate sphingolipid and lipid metabolism, and their role in lysosomal storage diseases.
• Review of the molecular mechanisms involved in lysosomal degradation and transport of lipids.
• Analysis of the relationship between lysosomal dysfunction and various diseases.
• Exploration of impacts on the nervous and immune systems due to sphingolipid accumulation.
• Lysosomal lipid degradation disorders can lead to various lysosomal storage diseases.
• Sphingolipid metabolism disturbances are linked to significant health issues, especially in the nervous and immune systems.
• Accumulation of sphingolipids in cells may trigger multiple lysosomal storage disorders.

Abstract