What question did this study set out to answer?

To investigate long-term alterations in large and medium-sized choroidal vessels in eyes affected by age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV).

April 10, 2026

Large and medium choroidal vessel remodelling in progressive age-related macular degeneration and polypoidal choroidal vasculopathy

Key Points

To investigate long-term alterations in large and medium-sized choroidal vessels in eyes affected by age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV).
Performed serial imaging using Indocyanine Green Angiography (ICGA) to examine choroidal vessels.
Compared changes in vessel structure over time between AMD and PCV cases.
Identified significant remodeling of large and medium choroidal vessels in eyes with AMD and PCV.
Vascular changes may be associated with the development of choroidal neovascular complexes.

Abstract

We report the long-term changes in large and medium-sized choroidal vessels in eyes with AMD and PCV with serial ICGA images. These vascular alterations suggest the possible role played by these vessels in the pathogenesis of choroidal neovascular complexes.

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Discussion

Authors

Ninan Jacob

Jay Chhablani

Umesh Chandra Behera

Journals

Retinal Cases & Brief Reports

Actions

Institutions

University of Pittsburgh Medical Center

L V Prasad Eye Institute

References and Citations

Connected Papers

Building similarity graph...

Analyzing shared references across papers

Large and medium choroidal vessel remodelling in progressive age-related macular degeneration and polypoidal choroidal vasculopathy

Key Points

Abstract

Citation Network

Connected Papers

Discussion

Authors

Journals

Actions

Institutions

References and Citations

Citation Network

Connected Papers

Discussion

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